City comparison
Chicago, IL is about 250 miles (425 km) from St. Louis, MO in a straight line. By road, the drive is roughly 325 miles, or about 5 h 30 min behind the wheel at highway speeds.
Driving distance is a rough estimate (great-circle × 1.25); driving time assumes a 60 mph blended average. Real trips run 10–20% longer with stops.
A direct flight from Chicago, IL to St. Louis, MO takes about 31 min, covering roughly 250 miles in a straight line. Connecting itineraries with a layover typically add 1–3 hours.
Block-to-block estimate at ~500 mph cruise, including taxi, climb, and descent — what an airline would publish, not pure airborne time.
Chicago has a population of 2,721,914, vs 298,018 in St. Louis — about 9.1× larger by population. By land area, Chicago covers about 230 sq mi vs 62 sq mi for St. Louis.
Population from US Census ACS. Land area from the Census Gazetteer (city proper, excluding inland water).
Cost indices by category, with the US city average (100) marked.
Index: 100 = US city average. Lower is more affordable.
Side-by-side costs, salaries, and sub-category indices.
| Metric | Chicago | St. Louis | Difference |
|---|---|---|---|
| Median rent | $1,314/mo | $938/mo | 40.1% higher in Chicago |
| Median home value | $304,500 | $174,100 | 74.9% higher in Chicago |
| Median household income | $71,673 | $52,941 | 35.4% higher in Chicago |
| Groceries index | 106.4 | 99.7 | 6.7% higher in Chicago |
| Utilities index | 84.4 | 71.9 | 17.4% higher in Chicago |
| Transportation index | 100.3 | 98.5 | 1.9% higher in Chicago |
| Healthcare index | 100.2 | 98.7 | 1.6% higher in Chicago |
How much you'd need to earn in the other city to keep the same standard of living.
If you earn $100,000 in Chicago, you'd need $84,097 in St. Louis to maintain your standard of living.
Climate, safety, and demographics side by side.
St. Louis, MO is about 15.9% cheaper overall than Chicago, IL, based on our cost-of-living index. Housing costs are roughly 42% higher in Chicago than in St. Louis. If you earn $80,000 in Chicago, you'd need about $67,278 in St. Louis to keep the same standard of living.