City comparison
Fort Myers, FL is about 1,000 miles (1,700 km) from San Antonio, TX in a straight line. By road, the drive is roughly 1,300 miles, or about 22 hours (about 2 days at 10 h/day) behind the wheel at highway speeds.
Driving distance is a rough estimate (great-circle × 1.25); driving time assumes a 60 mph blended average. Real trips run 10–20% longer with stops.
A direct flight from Fort Myers, FL to San Antonio, TX takes about 2 h 4 min, covering roughly 1,000 miles in a straight line. Connecting itineraries with a layover typically add 1–3 hours.
Block-to-block estimate at ~500 mph cruise, including taxi, climb, and descent — what an airline would publish, not pure airborne time.
Fort Myers, FL is on Eastern Time and San Antonio, TX is on Central Time — a 1-hour difference. When it's noon in Fort Myers, it's 11 a.m. in San Antonio, which puts Fort Myers 1 hours ahead.
Standard-time offsets. Daylight saving applies in both cities for most of the year (exceptions: Hawaii and most of Arizona), and the gap between the two stays the same.
San Antonio has a population of 1,445,662, vs 88,699 in Fort Myers — about 16.3× larger by population. By land area, San Antonio covers about 500 sq mi vs 40 sq mi for Fort Myers.
Population from US Census ACS. Land area from the Census Gazetteer (city proper, excluding inland water).
Cost indices by category, with the US city average (100) marked.
Index: 100 = US city average. Lower is more affordable.
Side-by-side costs, salaries, and sub-category indices.
| Metric | Fort Myers | San Antonio | Difference |
|---|---|---|---|
| Median rent | $1,322/mo | $1,189/mo | 11.2% higher in Fort Myers |
| Median home value | $318,900 | $198,000 | 61.1% higher in Fort Myers |
| Median household income | $57,403 | $59,593 | 3.8% higher in San Antonio |
| Groceries index | 96.5 | 94.2 | 2.4% higher in Fort Myers |
| Utilities index | 87.6 | 83.3 | 5.2% higher in Fort Myers |
| Transportation index | 99.0 | 96.6 | 2.5% higher in Fort Myers |
| Healthcare index | 98.5 | 96.1 | 2.5% higher in Fort Myers |
How much you'd need to earn in the other city to keep the same standard of living.
If you earn $100,000 in Fort Myers, you'd need $87,305 in San Antonio to maintain your standard of living.
Climate, safety, and demographics side by side.
San Antonio, TX is about 12.7% cheaper overall than Fort Myers, FL, based on our cost-of-living index. Housing costs are roughly 30% higher in Fort Myers than in San Antonio. If you earn $80,000 in Fort Myers, you'd need about $69,844 in San Antonio to keep the same standard of living.